WEBINAR:

Claude Science + Biologics LIMS: from sequence variant to documented lead candidate

Watch 12 antibody variants go from sequence alignment to lead candidate to ELN entry.

September 9th @ 9:00AM Pacific  |  30 Minutes

Presenter: 

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Bernard Lee
Product Manager

Claude Science can run your protein engineering analysis. Whether you can trust the results depends on the data model it's connected to.

In 30 minutes we connect Claude Science to LabKey Biologics LIMS over MCP and put it to work on a real problem: 12 sequence variants, aligned to the parent, and screened for binding and neutralization.

We'll walk through how Biologics LIMS makes this analysis possible in Claude Science: molecules, sequences, samples, assay results, and inventory, each registered with a stable ID and connected by modeled relationships.

You'll see which queries the agent runs, which relationships it follows, and how every figure traces back to Biologics LIMS as the system of record.

What you'll see in Claude Science and Biologics LIMS:

  • A sequence variant set aligned against its parent in Claude Science, with substitutions resolved from the bioregistry rather than from a FASTA file someone maintained by hand.

  • Binding and neutralization data pulled by molecule, already joined to the samples and constructs that produced it, then plotted without a manual merge step.

  • Inventory queried in the same session, confirming which variants have enough material and where the vials sit before anyone commits to a follow-up experiment.

  • Analyses and a written lead-candidate rationale posted back into the ELN through the LabKey API, closing data, analysis, and documented conclusion inside one system.

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On the agenda: 

Connecting Claude Science to Biologics LIMS over MCP: what the connection reads and the Biologics LIMS data model that makes Claude Science work

Variants and alignment: Claude Science pulls the molecules in the environment, isolates the sequence variants, and aligns them against the parent, rendering the alignment natively

Assay data and visualisation: retrieving the binding and neutralization results already linked to those samples, then building the plots that make variant performance comparable

Findings: the figures and a short summary of the standout variants, the hardest target, and the lead candidate

Inventory reality check: remaining quantities and storage locations confirmed for those candidates, in the same conversation

Write-back: figures and the lead-candidate rationale posted into the ELN through the LabKey API

Q&A and next steps for learning more about LabKey Biologics LIMS and Claude Science

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